Continuous Manufacturing
Gericke Formulation Skid GFS
The Gericke Formulation Skid GFS is a fully automated continuous manufacturing method for blending excipients and API upstream compaction, available in two versions: Continuous or Mini-Batch-Blending. It combines high precision loss-in-weight feeders with scientifically designed compact blenders and integrated PAT solutions.
Gericke Formulation Skid GFS
See the Gericke Formulation Skid GFS for Continuous Manufacturing of Oral Solid Dosages OSD at the new FAT centre of Gericke in Switzerland.
Paradigm shift in pharmaceutical to continuous manufacturing
Most pharmaceutical granules and tablets are produced in batches, not just when preparing the raw components in accordance with the formula but also when mixing the excipients with the active ingredients
After a long period during which the traditional batch process dominated the pharmaceutical manufacturing of OSD, the Food and Drug Administration and the European Medicines recognized the advantages of continuous manufacturing. This removed the regulatory barriers, which historically had held back the increased use of continuous feeding and blending processes in the manufacture of drugs.
The Gericke Formulation Skid can easily be integrated into your existing solid dosage form processes such as:
- Direct Compression
- Wet or Dry Granulation
- Hot Melt Extrusion
- Sachet or Capsule Filling
- As individual unit operation for formulation development
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