Gericke Formulation Skid GFS
The Gericke Formulation Skid (GFS) offers fully automated continuous or mini-batch blending of excipients and APIs. It features high-precision loss-in-weight feeders, compact blenders, and integrated PAT solutions for efficient, error-free downstream compaction.
Gericke Formulation Skid GFS
Swiss Army Knife of Continuous Manufacturing
Our equipment offers unparalleled flexibility, making it ideal for both early development and seamless integration with upstream and downstream processes in continuous manufacturing. The modular design, featuring interchangeable feeders, accommodates a wide range of materials and throughput rates.
Advantages
- Vendor-Neutral Approach: Capable of optimal integration of various downstream equipment.
- Modular Design: Features up to 7 interchangeable feeders to accommodate various materials and throughput rates.
- Seamless Integration: Supports continuous manufacturing from early formulation development to full-scale production.
- Unparalleled Flexibility and Adaptability: Can be used as standalone equipment or integrated with various upstream and downstream processes.
Your Benefits
- Lower Operational Cost: With our advanced automation System coupled and our continuous formulation skid you can save up to 48% of operational cost.
- Save on Precious Resources: Minimize waste of costly APIs and optimize energy input without compromising on quality.
- Increase Profitability: Save time by seamlessly scaling from development to commercial manufacturing with our technology.
Pharma Feeders
High Precision Loss-in-Weight Feeders
Combining gravimetric feeding with advanced weighing and control systems ensures precise batch or continuous mass flow. Our high-accuracy load cells dynamically adjust the feed rate, ranging from as little as 0.05 kg/h to 500 kg/h, guaranteeing consistent and accurate delivery.
Advantages
- Adaptability: Various sizes to match your desired feed rate
- Intuitive Operation: Intuitive and easy-to-use HMI ensures seamless operation and enhances user experience
- Hygenic Design: WIP-capable and high containment (up to OEB 5)
Benefits
- Save Cost: Highest feeding accuracy even for difficult flowing products allow for narrow feeding tolerance windows thus reducing waste.
- Time Saving: Our user-friendly design and enables quick cleaning through efficient dissambly / reassembly.
- Reliability and Safety: Consistent and precise dosing combined with built-in control mechanisms assure highest product quality every single time.
Pharma Mini Blender GBM
Compact Blender for High Potency Drugs
Merging batch processing with continuous production for low dosage, low volume, and highly potent products. It excels in highly potent drugs and personalized medicine, ensuring top mixing quality even at low API contents and small batch sizes, anything from <1 kg/h to 50 kg/h.
Advantages
- High Potency Drugs: Maximal mixing homogeneity even at low API concentrations (< 1% API concentrations)
- Space-Saving: Our compact machine fits seamlessly into any space (-83% GMP Area!) without compromising on throughput, ensuring maximum efficiency and productivity.
- Flexible & Adaptable: The blender can operate in batch-mode or continuous mode and be used as a standalone machine or intergrated at a later point into our Gericke Formulation Skid
Benefits
- Reduced Development Cost: The option of small batches without any start-up losses allow for significantly quicker processing, lower variability and faster feedback.
- Plug-N-Play: Extremely easy and inuitive HMI to operate the machine – no training required.
- Significant Time Saving: Homogeneity is achieved 40% faster compared to traditional mixing methods.
Pharma Continuous Blender GCM
Scaleable and Lean Mixing Technology
Offering high homogeneity with adjustable residence time and energy input, our GCM blenders maintain uniformity in continuous feeding and mixing of challenging powders. Its throughput ranges from 1 kg/h to 1’000 kg/h.
Advantages
- Large Throughput Range: Accurate continuous mixing capacities start at 1 kilo per hour and can be scaled up to 1 ton per hour, allowing for easy scale-up without revalidation.
- Versatile & Hygienic Design: Removable mixing tool and housing enable fast and hygienic cleaning.
Benefits
- Save Facility Cost: Compared to traditional methods, our GCM solution requires 83% less GMP area! And delivers the power and throughput you need, in the fraction of the space.
- Save Precious Resources: Thanks to the start-up valve, waste is significantly reduces compared to traditional continuous blenders, in addition to saving you 75% of energy per kg of product.
Pharma Sampling Valve GSV
Real Time Quality Control with PAT
Working in a fully automated fashion, it is the only sampler on the market to assess the complete cross-sectional probe, providing a representative sample and a precise, reliable quality assurance.
Advantages
- Precision: Representative sampling ensuring output meets quality standards.
- Integration: Seamlessly integrates with existing continuous manufacturing systems.
- Compliance: Fully cGMP compliant
- Efficiency: Adjustable sampling size to meet unit dose, minimizing material waste
- Versatility: Suitable for a wide range of OSD forms and manufacturing setups.
- Safety: Suitable for high containment applications with Wash-in-Place option
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